Association of Metabolomics With Incidence of Age-Related Macular Degeneration: The UK Biobank Study
Our findings reveal significant associations between specific metabolites and AMD incidence, highlighting the roles of lipoprotein subclasses, cholesterol subtypes, apolipoproteins, glucose, and albumin. Although metabolomics did not improve risk prediction, certain biomarkers may serve as promising therapeutic targets.
Authors
- Xiu Juan Zhang (ORCID: https://orcid.org/0000-0002-4197-1423)
- Ka Wai Kam (ORCID: https://orcid.org/0000-0002-7760-6882)
- Clement Chee Yung Tham (ORCID: https://orcid.org/0000-0003-4407-6907)
- Jason C. S. Yam (ORCID: https://orcid.org/0000-0002-2156-1486)
- Li Jia Chen (ORCID: https://orcid.org/0000-0003-3500-5840)
- Alvin Lerrmann Young (ORCID: https://orcid.org/0000-0002-4365-3218)
- Mary Ho (ORCID: https://orcid.org/0000-0001-8864-2988)
- Chi Pui Pang (ORCID: https://orcid.org/0000-0002-7764-6382)
- Jun Qing Yu (ORCID: https://orcid.org/0000-0001-5008-2153)
- Yuzhou Zhang (ORCID: https://orcid.org/0000-0001-8515-3388)
Institutions
- Chinese University of Hong Kong (HK)
- Hong Kong Eye Hospital (CN)
- Prince of Wales Hospital (CN)
- University of Hong Kong (HK)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2024-12-31
- DOI
- https://doi.org/10.1167/iovs.65.14.43
- Citations
- 5
- Primary Topic
- Retinal Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.69
Funders
- Hong Kong Government
- Health and Medical Research Fund