Topographical Quantification of Hyper-Reflective Foci May Predict the Development of Macular Atrophy in Patients With Neovascular Age-Related Macular Degeneration
After only 1 year of antiangiogenic therapy, there was a significant decrease in HRFs observed across all retinal layers. This reduction persisted even after 2 years of anti-VEGF treatment. Notably, the quantity of HRFs in the outer retina at baseline exhibited a correlation with the development of macular atrophy that endured at both the 1-year and 2-year follow-ups after anti-VEGF treatment.
Authors
- Giuseppe Giannaccare (ORCID: https://orcid.org/0000-0003-2617-0289)
- Enrico Borrelli (ORCID: https://orcid.org/0000-0003-2815-5031)
- Michele Santoro (ORCID: https://orcid.org/0000-0003-0676-3036)
- Maria Oliva Grassi (ORCID: https://orcid.org/0000-0002-5952-7910)
- Michele Reibaldi (ORCID: https://orcid.org/0000-0003-1368-6729)
- Pasquale Viggiano (ORCID: https://orcid.org/0000-0002-0323-967X)
- Francesco Boscia (ORCID: https://orcid.org/0000-0002-5478-060X)
- Giovanni Petrara
- Giacomo Boscia
- Giovanni Alessio
- Ciro Borriello
Institutions
- University of Cagliari (IT)
- University of Turin (IT)
- University of Bari Aldo Moro (IT)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2024-12-31
- DOI
- https://doi.org/10.1167/iovs.65.14.45
- Citations
- 4
- Primary Topic
- Retinal Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.15