Potential Contribution of Epithelial Growth Factor Receptor to PI3K/AKT Pathway Dysregulation in Canine Soft Tissue Sarcoma

EGFR over-expression, rather than PTEN loss or PIK3CA mutations, may contribute to PI3K/AKT pathway dysregulation in canine STS. Further studies with larger sample sizes and additional validation techniques are necessary to confirm these findings.

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Publication Details

Journal
In Vivo
Published
2024-12-31
DOI
https://doi.org/10.21873/invivo.13808
Citations
2
Primary Topic
Veterinary Oncology Research
Type
article
Field-Weighted Citation Impact
0.84
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article

Potential Contribution of Epithelial Growth Factor Receptor to PI3K/AKT Pathway Dysregulation in Canine Soft Tissue Sarcoma

Alfarisa Nururrozi, Yusuke Sakai, Takuya Mizuno, Masaya Igase et al.
2 citations
In Vivo
Veterinary Oncology Research
0.84
article

Potential Contribution of Epithelial Growth Factor Receptor to PI3K/AKT Pathway Dysregulation in Canine Soft Tissue Sarcoma

Alfarisa Nururrozi, Yusuke Sakai, Takuya Mizuno, Masaya Igase, Masashi Sakurai, Kyohei Miyanishi, Mika Tanabe
article en
2 citations

Abstract

EGFR over-expression, rather than PTEN loss or PIK3CA mutations, may contribute to PI3K/AKT pathway dysregulation in canine STS. Further studies with larger sample sizes and additional validation techniques are necessary to confirm these findings.

In VivoVol. 39(1)
Universitas Gadjah Mada (ID), Yamaguchi University (JP), Veterinary Medical Center (JP)
Openalex Percentile: Top 22%
Veterinary Oncology Research
0.84
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