Unilateral Bleomycin-induced Interstitial Pneumonitis Mouse Model With Both a Healthy and a Diseased Lung

Establishing both a healthy and a diseased lung in the same individual model was feasible, achieving lessened body weight loss and more favorable survival. This technique allows for a more efficacious research design, where both the efficacy and adverse effects of a pharmaceutical agent can be evaluated in a single animal.

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Publication Details

Journal
In Vivo
Published
2024-12-31
DOI
https://doi.org/10.21873/invivo.13823
Citations
2
Primary Topic
Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
Type
article
Field-Weighted Citation Impact
0.84
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article

Unilateral Bleomycin-induced Interstitial Pneumonitis Mouse Model With Both a Healthy and a Diseased Lung

Keigo Osuga, Eisuke Ueshima, HIROSHI KODAMA, Koichiro Yamakado et al.
2 citations
In Vivo
Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
0.84
article

Unilateral Bleomycin-induced Interstitial Pneumonitis Mouse Model With Both a Healthy and a Diseased Lung

Keigo Osuga, Eisuke Ueshima, HIROSHI KODAMA, Koichiro Yamakado, Yutaka Hirata, HARUYUKI TAKAKI, Yasushi Kimura, Reona Wada
article en
2 citations

Abstract

Establishing both a healthy and a diseased lung in the same individual model was feasible, achieving lessened body weight loss and more favorable survival. This technique allows for a more efficacious research design, where both the efficacy and adverse effects of a pharmaceutical agent can be evaluated in a single animal.

In VivoVol. 39(1)
Kobe University (JP), Hyogo University (JP), Osaka University of Pharmaceutical Sciences (JP), The University of Osaka (JP)
Zero hunger, Good health and well-being
Openalex Percentile: Top 22%
Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
0.84
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