Construction of diaryl oxacyclic sulfones <i>via</i> Bi(OTf) <sub>3</sub> -catalyzed intramolecular cyclocondensation of 1,3-diaroylsulfones
We report the synthesis of six-membered saturated and unsaturated 1,4-oxasulfone derivatives <i>via</i> rongalite-mediated intermolecular double sulfination of α-bromoacetophenone. This was followed by Bi(OTf)<sub>3</sub>-catalyzed intramolecular condensation of 1,3-diaroylsulfones under open-vessel conditions. Furthermore, the chemical structures of the key products were determined through single-crystal X-ray analyses.
Authors
- Meng‐Yang Chang (ORCID: https://orcid.org/0000-0002-1983-8570)
- Chun-Yi Lin (ORCID: https://orcid.org/0000-0001-8802-3677)
Institutions
- Kaohsiung Medical University (TW)
- National Pingtung University of Science and Technology (TW)
- Kaohsiung Medical University Chung-Ho Memorial Hospital (TW)
Publication Details
- Journal
- Organic & Biomolecular Chemistry
- Published
- 2024-12-30
- DOI
- https://doi.org/10.1039/d4ob01916d
- Citations
- 2
- Primary Topic
- Sulfur-Based Synthesis Techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.50
Funders
- National Science Council