Development of correction techniques for the J-PET scanner

<b>Objective:</b> Positron emission tomography (PET) is a widely used medical imaging technique that allows for non-invasive imaging of metabolic processes. However, traditional PET scanners rely on costly inorganic scintillators that limit their accessibility, especially in light of emerging long axial field-of-view devices. The modular J-PET scanner, an innovative alternative, uses 50-cm-long plastic scintillator strips, offering a cost-effective and modular solution. In this study we develop and assess the PET data correction techniques required for quantitative image reconstruction. <br><b>Methods:</b> We present methods for attenuation correction, random coincidence correction using the delayed time window (DTW) technique and scatter correction based on Monte Carlo simulations. Phantom studies using the NEMA IQ phantom were performed to qualitatively evaluate these corrections. <br><b>Results:</b> The results demonstrate that our implemented corrections for attenuation and random and scattered coincidences successfully improve the uniformity of tracer distribution in homogenous volumes and significantly reduce undesired activity in cold regions. Despite limitations in sensitivity and axial resolution, the applied correction techniques effectively enhance image quality, providing promising results for future applications. <br><b>Conclusions:</b> These findings highlight the potential of the modular J-PET system to offer affordable PET imaging and to pave the way for a total-body PET scanner based on plastic scintillators. Future work will focus on quantitative validation and the implementation of these corrections for human subject imaging.

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Publication Details

Journal
Bio-Algorithms and Med-Systems
Published
2024-12-27
DOI
https://doi.org/10.5604/01.3001.0054.9362
Citations
6
Primary Topic
Medical Imaging Techniques and Applications
Type
article
Field-Weighted Citation Impact
2.43

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article

Development of correction techniques for the J-PET scanner

T. Kaplanoglu, D. Kumar, Martin Rädler, Catalina Curceanu et al.
6 citations
Bio-Algorithms and Med-Systems
Medical Imaging Techniques and Applications
2.43
article

Development of correction techniques for the J-PET scanner

T. Kaplanoglu, D. Kumar, Martin Rädler, Catalina Curceanu, Keyvan Tayefi Ardebili, M. Skurzok, Alicja Hubalewska‐Dydejczyk, Kamila Kasperska, E. Czerwiński, Edward Lisowski, Bogusław Głowa, Piyush Pandey, G. Korcyl, Szymon Niedźwiecki, E. Y. Beyene, Karol Kubat, Manish Das, Kavya Valsan Eliyan, Ramsey Derek Badawi, S. Parzych, P. Tanty, A. Khreptak, Anna Sowa‐Staszczak, Simbarashe Moyo, Marta Opalińska, N. Chug, K. Kacprzak, Justyna Mędrala, Reimund Bayerlein, Ewa Łucja Stępień, W. Mryka, S. Sharma, Filip Lisowski, Benjamin A. Spencer, Anoop Kunimmal Venadan
article en
6 citations

Abstract

<b>Objective:</b> Positron emission tomography (PET) is a widely used medical imaging technique that allows for non-invasive imaging of metabolic processes. However, traditional PET scanners rely on costly inorganic scintillators that limit their accessibility, especially in light of emerging long axial field-of-view devices. The modular J-PET scanner, an innovative alternative, uses 50-cm-long plastic scintillator strips, offering a cost-effective and modular solution. In this study we develop and assess the PET data correction techniques required for quantitative image reconstruction. <br><b>Methods:</b> We present methods for attenuation correction, random coincidence correction using the delayed time window (DTW) technique and scatter correction based on Monte Carlo simulations. Phantom studies using the NEMA IQ phantom were performed to qualitatively evaluate these corrections. <br><b>Results:</b> The results demonstrate that our implemented corrections for attenuation and random and scattered coincidences successfully improve the uniformity of tracer distribution in homogenous volumes and significantly reduce undesired activity in cold regions. Despite limitations in sensitivity and axial resolution, the applied correction techniques effectively enhance image quality, providing promising results for future applications. <br><b>Conclusions:</b> These findings highlight the potential of the modular J-PET system to offer affordable PET imaging and to pave the way for a total-body PET scanner based on plastic scintillators. Future work will focus on quantitative validation and the implementation of these corrections for human subject imaging.

Bio-Algorithms and Med-SystemsVol. 20(1)
Jagiellonian University (PL), Cracow University of Technology (PL), Istituto Nazionale di Fisica Nucleare, Laboratori Nazionali di Frascati (IT), University of California, Davis (US)
National Institutes of Health
Industry, innovation and infrastructure
Openalex Percentile: Top 10%
Medical Imaging Techniques and Applications
2.43
DOIOpen Access PDFOpenAlex
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