Detection of porphyromonas gingivalis in oral potentially malignant disorders and oral squamous cell carcinoma using qRT-PCR: A comparative study

Our findings suggest that there is an over expression of <i>P. gingivalis</i> in oral potentially malignant disorders and oral squamous cell carcinoma, compared to normal mucosa and highly expressed in OSCCs compared to OPMD. Increased levels of <i>P. gingivalis</i> in OPMDs and OSCCs may suggest the early event of tumorigenesis. Hence, it can be used as a valuable marker for early diagnosis, prognosis marker and in the identification of therapeutic targets.