Strain-limited biofilm regulation through the Brg1-Rme1 circuit in <i>Candida albicans</i>

<i>Candida albicans</i> is a widespread fungal pathogen. The regulatory circuitry underlying virulence traits is well studied in the reference strain background, but not in other clinical isolate backgrounds. Here, we describe a pronounced example of strain variation in the control of two prominent virulence traits, biofilm formation and filamentation.

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Publication Details

Journal
mSphere
Published
2024-12-31
DOI
https://doi.org/10.1128/msphere.00980-24
Citations
1
Primary Topic
Antifungal resistance and susceptibility
Type
article
Field-Weighted Citation Impact
0.39

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article

Strain-limited biofilm regulation through the Brg1-Rme1 circuit in Candida albicans

Aaron P. Mitchell, Min-Ju Kim
1 citations
mSphere
Antifungal resistance and susceptibility
0.39
article

Strain-limited biofilm regulation through the Brg1-Rme1 circuit in Candida albicans

Aaron P. Mitchell, Min-Ju Kim
article en
1 citations

Abstract

<i>Candida albicans</i> is a widespread fungal pathogen. The regulatory circuitry underlying virulence traits is well studied in the reference strain background, but not in other clinical isolate backgrounds. Here, we describe a pronounced example of strain variation in the control of two prominent virulence traits, biofilm formation and filamentation.

mSphereVol. 10(1)
University of Georgia (US)
University of Georgia, National Institutes of Health, National Institute of Allergy and Infectious Diseases
Openalex Percentile: Top 33%
Antifungal resistance and susceptibility
0.39
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