Electroacupuncture pretreatment at ST36 alleviates acute gastric mucosal lesions induced by water immersion restraint stress through the TRPV1/SP/CGRP/NO pathway in rats
The TRPV1 signaling pathways likely play an important role in the pathogenesis of AGML. In addition, EA pretreatment protected gastric mucosa lesions induced by WIRS by reducing the expression of TRPV1/SP in the DRG and gastric mucosa, as well as up-regulating gastric CGRP/NO. Antioxidant mechanisms are likely to at least partially mediate the protective effects of EA against AGML.
Authors
- Mingyan Guo (ORCID: https://orcid.org/0000-0003-1353-1487)
- Weifeng Tu (ORCID: https://orcid.org/0000-0003-2396-7145)
- Chuangbo Xie
- Xiangyu Li (ORCID: https://orcid.org/0000-0003-1943-846X)
- Liang Guo (ORCID: https://orcid.org/0000-0003-2111-0631)
- Qun Jiang (ORCID: https://orcid.org/0000-0003-2251-4515)
- Qiong Ling
- Gaofeng Zhao
Institutions
- Guangzhou University of Chinese Medicine (CN)
- Sun Yat-sen University (CN)
- Sun Yat-sen Memorial Hospital (CN)
- General Hospital of Guangzhou Military Command (CN)
- Guangdong Provincial Hospital of Traditional Chinese Medicine (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- Acupuncture in Medicine
- Published
- 2024-12-31
- DOI
- https://doi.org/10.1177/09645284241300177
- Primary Topic
- Acupuncture Treatment Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00