Drug Delivery in PROSE Device as Alternative to Frequent Drop Administration in Severe Ocular Surface Disease
The design of the prosthetic replacement of the ocular surface ecosystem (PROSE) device allows it to serve as a novel drug delivery system. In this article, we describe the off-label administration of amphotericin B and cenegermin by instillation in the PROSE device reservoir for the treatment of Candida keratitis in the setting of a persistent epithelial defect.
Authors
- Deborah S. Jacobs (ORCID: https://orcid.org/0000-0002-8587-1184)
- Yandong Bian
Institutions
- Massachusetts Eye and Ear Infirmary (US)
- Deaconess Hospital (US)
- Jacobs (United States) (US)
Publication Details
- Journal
- Eye & Contact Lens Science & Clinical Practice
- Published
- 2024-12-31
- DOI
- https://doi.org/10.1097/icl.0000000000001163
- Primary Topic
- Ocular Surface and Contact Lens
- Type
- article
- Field-Weighted Citation Impact
- 0.00