RBM47 promotes cell proliferation and immune evasion by upregulating PDIA6: a novel mechanism of pancreatic cancer progression
In summary, our findings demonstrate that RBM47 contributes to PC progression, which might be mediated by the upregulated PDIA6 expression and the altered cellular metabolites in PC cells, offering a potential therapeutic target for PC treatment.
Authors
- Huijie Fan (ORCID: https://orcid.org/0000-0003-4298-0679)
- Chenfei Li
- Enjie Liu
- Pei Huang (ORCID: https://orcid.org/0000-0003-2735-7758)
- Meiying Cui (ORCID: https://orcid.org/0000-0003-4191-715X)
- Jing Wen Zhou (ORCID: https://orcid.org/0000-0001-8336-7278)
- Zhengyang Wang (ORCID: https://orcid.org/0000-0002-4906-5708)
- Yihui Ma (ORCID: https://orcid.org/0000-0003-2782-394X)
- Kuisheng Chen (ORCID: https://orcid.org/0000-0003-0610-310X)
Institutions
- First Affiliated Hospital of Zhengzhou University (CN)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2024-12-31
- DOI
- https://doi.org/10.1186/s12967-024-05970-6
- Citations
- 4
- Primary Topic
- Immune Cell Function and Interaction
- Type
- article
- Field-Weighted Citation Impact
- 0.96
Funders
- National Natural Science Foundation of China