Clinical and experimental substantiation of the effectiveness of non-pigmented laser photoablation in the treatment of peri-implantitis

INTRODUCTION. In the treatment of peri-implantitis, it is important to significantly relieve inflammation in the peri-implant area, stop bone resorption and stimulate tissue regeneration. This is possible when using laser radiation with the effects of pigment-free laser photoablation. AIM . Improving the effectiveness of peri-implantitis treatment using pigment-free laser photoablation. MATERIALS AND METHODS. An experimental comparative study in 28 animals with model peri-implantitis under the influence of laser radiation with pigment-free photoablation and mechanical treatment of the periimplant area in equal groups. Treatment of 70 patients with peri-implantitis in 2 equal groups of 35 patients – using pigment-free laser photoablation and mechanical treatment. In the groups, the immediate and remote results were assessed according to clinical signs. Before and after treatment, laboratory analysis of C-reactive protein, S-IgA and cortisol was performed. RESULTS. Morphological analysis showed that the use of pigment-free laser photoablation helps to reduce inflammation and accelerate tissue regeneration. Clinical analysis showed high efficiency of pigment-free laser photoablation by 3.2 times compared to mechanical treatment. Analysis of laboratory research showed that the use of pigment-free laser photoablation helps to reduce CRP by 7.6, stimulate S-IgA by 1.2 times, stimulate cortisol by 1.3 times compared to traditional mechanical and drug treatment of peri-implant pockets. CONCLUSIONS. Our experimental and clinical laboratory studies confirm the need to use pigment-free laser photoablation to improve the effectiveness of peri-implantitis treatment