InPAS: An R/Bioconductor Package for Identifying Novel Polyadenylation Sites and Alternative Polyadenylation from Bulk RNA-seq Data

InPAS is an efficient and robust tool for identifying and quantifying APA events using readily accessible conventional RNA-seq data. Its versatility opens doors to explore APA regulation across diverse eukaryotic systems with various experimental designs. We believe that InPAS will drive APA research forward, deepening our understanding of its role in regulating gene expression, and potentially leading to the discovery of biomarkers or therapeutics for diseases.

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Publication Details

Journal
Frontiers in Bioscience-Scholar
Published
2024-12-17
DOI
https://doi.org/10.31083/j.fbs1604021
Primary Topic
RNA Research and Splicing
Type
article
Field-Weighted Citation Impact
0.00

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article

InPAS: An R/Bioconductor Package for Identifying Novel Polyadenylation Sites and Alternative Polyadenylation from Bulk RNA-seq Data

Sungmi Park, Michael Richard Green, Lihua Julie Zhu, Jianhong Ou et al.
2 links
Frontiers in Bioscience-Scholar
RNA Research and Splicing
article

InPAS: An R/Bioconductor Package for Identifying Novel Polyadenylation Sites and Alternative Polyadenylation from Bulk RNA-seq Data

Sungmi Park, Michael Richard Green, Lihua Julie Zhu, Jianhong Ou, Haibo Liu
article en

Abstract

InPAS is an efficient and robust tool for identifying and quantifying APA events using readily accessible conventional RNA-seq data. Its versatility opens doors to explore APA regulation across diverse eukaryotic systems with various experimental designs. We believe that InPAS will drive APA research forward, deepening our understanding of its role in regulating gene expression, and potentially leading to the discovery of biomarkers or therapeutics for diseases.

Frontiers in Bioscience-ScholarVol. 16(4)
University of Massachusetts Chan Medical School (US), Duke University (US)
National Institutes of Health
Openalex Percentile: Top 79%
RNA Research and Splicing
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