Relationship Between Autism Spectrum Disorder And The Brain-Gut Axis

ABSTRACT All of the microorganisms that live in the intestines are called the microbiota. Metabolites and molecules produced by the microbiota can affect the nervous system and help regulate how the brain works. Communication between the gut and the brain is mediated by the microbiota, the brain-gut axis. There is some evidence to suggest that changes in the microbiota may be associated with autism spectrum disorder (ASD). It is also thought that changes in the microbiota may have an impact on brain function. Studies show that there is an altered microbiota profile in individuals with ASD compared to the normal population. Individuals with autism may have different gut microbiota communities and reduced overall microbiota diversity. However, whether these changes cause or result from autism has not yet been fully established. Research into the causes and treatment of ASDs continues, and this area of research has promising potential and may contribute to the development of new treatment approaches for individuals with ASDs in the future.