Comparative Study of Lipid Profile and ABO Blood Grouping

The relationship between ABO blood groups and lipid profiles is gaining attention due to its potential implications for understanding cardiovascular disease risk and metabolic health. This study is aimed at assessing the relationship between the lipid profile of apparently healthy individuals with different ABO blood groups. The subjects used in this project were apparently healthy individuals of different ABO blood groups from Ambrose Alli University, Ekpoma, Edo State. We recruited a total of one hundred and sixty (160) subjects for this study, including thirty (30) from blood groups A, B, AB, and O. The results obtained show that the level of total cholesterol was higher in blood groups A (85.13±20.58 mg/dl) and B (89.08±17.19 mg/dl) compared to blood groups AB (81.00±11.65 mg/dl) and O (83.80±15.87 mg/dl). This increase was not statistically significant (p > 0.05). The level of triglyceride was higher in blood groups A (171.40±20.37) and B (170.40±18.36 mg/dl) compared to blood groups AB (169.90±15.80 mg/dl) and O (166.70±14.89 mg/dl). Also, the level of HDL was higher in blood group A (50.23±5.36 mg/dl) and B (51.60±5.17 mg/dl) compared to blood group AB (48.55±5.56 mg/dl) and O (49.88±5.55 mg/dl). Furthermore, levels of LDL were higher in blood groups A (104.35±16.91 mg/dl) and AB (105.80±13.88 mg/dl) compared to blood groups B (101.30±15.62 mg/dl) and O (100.33±12.54 mg/dl). From the results obtained in this study, it is evident that there was no significant difference in the levels of total cholesterol, triglycerides, HDL, and LDL within the different ABO blood group systems. Therefore, it could be concluded that lipid profile remained unaltered in blood groups A, B, AB, and O.