Impact of neurotoxicity and steroid therapy on cancer progression-free survival in lymphoma patients treated with anti-CD19 CAR T cells
Our findings suggest that ICANS and steroid therapy do not adversely impact the PFS in lymphoma patients receiving anti-CD19 CAR T cells. Yet, ICANS might be associated with reduced early OS.
Authors
- Umberto Pensato (ORCID: https://orcid.org/0000-0002-4042-4735)
- Lorenzo Muccioli (ORCID: https://orcid.org/0000-0001-6827-0099)
- Simona Marcheselli (ORCID: https://orcid.org/0000-0002-7238-4088)
- Maria Guarino (ORCID: https://orcid.org/0000-0002-8894-2187)
- Federica Pondrelli (ORCID: https://orcid.org/0000-0002-0241-4587)
- Gianmarco Bagnato
- Chiara De Philippis (ORCID: https://orcid.org/0000-0002-7738-997X)
- Gian Maria Asioli (ORCID: https://orcid.org/0000-0002-1288-8102)
- Stéfania Bramanti (ORCID: https://orcid.org/0000-0002-4117-7991)
- Daniele Mannina (ORCID: https://orcid.org/0000-0002-1378-6896)
- Daniela Taurino (ORCID: https://orcid.org/0009-0009-0276-8295)
- Francesca Bonifazi (ORCID: https://orcid.org/0000-0003-1544-9911)
- Pier Luigi Zinzani (ORCID: https://orcid.org/0000-0002-2112-2651)
Institutions
- Humanitas University (IT)
- Istituto di Ematologia di Bologna (IT)
- Istituto delle Scienze Neurologiche di Bologna (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- IRCCS Humanitas Research Hospital (IT)
- University of Bologna (IT)
Publication Details
- Journal
- Neuro-Oncology Practice
- Published
- 2024-12-31
- DOI
- https://doi.org/10.1093/nop/npae128
- Primary Topic
- CAR-T cell therapy research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Dipartimento di Scienze Mediche, Università degli Studi di Torino
- Università di Bologna
- Humanitas University
- Humanitas Research Hospital