Use of Epic <sup>®</sup> to facilitate high-quality randomization of emergency department-based pragmatic clinical trials
Integration of blinded randomization schemes into electronic health record systems resulted in high-volume balanced enrollment of participants 24 h per day while maintaining concealed allocation. Use of this technology is an important tool to scale performance of high-quality pragmatic trials in emergency department settings while minimizing bias.
Authors
- Jeremiah S. Hinson (ORCID: https://orcid.org/0000-0002-2024-2360)
- Douglas A.E. White (ORCID: https://orcid.org/0000-0002-5979-8008)
- Richard E. Rothman (ORCID: https://orcid.org/0000-0002-1017-9505)
- James Galbraith (ORCID: https://orcid.org/0000-0003-4325-3836)
- Sarah E. Rowan (ORCID: https://orcid.org/0000-0003-2144-7410)
- Emily Hopkins (ORCID: https://orcid.org/0000-0001-7591-493X)
- Jason S. Haukoos (ORCID: https://orcid.org/0000-0001-7784-6811)
- Matthew Toerper (ORCID: https://orcid.org/0000-0003-0605-5339)
- Scott Levin (ORCID: https://orcid.org/0000-0002-7143-7635)
- Michael S. Lyons (ORCID: https://orcid.org/0000-0002-4774-1899)
- Yu-Hsiang Hsieh
Institutions
- Johns Hopkins University (US)
- Colorado School of Public Health (US)
- Alameda Health System (US)
- Denver Health Medical Center (US)
- Jackson Memorial Hospital (US)
- University of Mississippi Medical Center (US)
- Highland Hospital (US)
- Denver Public Health (US)
- Public Health Institute (US)
- Beckman Coulter Foundation (US)
- University of Colorado Anschutz Medical Campus (US)
- The Ohio State University (US)
- University of Cincinnati (US)
- University of Cincinnati Medical Center (US)
- University of Colorado Denver (US)
Publication Details
- Journal
- Clinical Trials
- Published
- 2024-12-29
- DOI
- https://doi.org/10.1177/17407745241301998
- Citations
- 2
- Primary Topic
- Meta-analysis and systematic reviews
- Type
- article
- Field-Weighted Citation Impact
- 0.92
Funders
- National Institute on Drug Abuse
- National Institute of Allergy and Infectious Diseases