Mismatch repair, p53, and L1 cell adhesion molecule status influence the response to chemotherapy in advanced and recurrent endometrial cancer
In chemotherapy-naïve patients with advanced and recurrent EC, there was a better prognosis in the order of MMR-D, p53wt/pMMR, and p53abn tumors after chemotherapy. L1CAM status is useful as a new marker to stratify p53wt/pMMR in advanced and recurrent groups.
Authors
- Eun Ji Nam (ORCID: https://orcid.org/0000-0003-0189-3560)
- Byungsoo Ahn (ORCID: https://orcid.org/0009-0007-3641-9590)
- Sang Wun Kim (ORCID: https://orcid.org/0000-0002-8342-8701)
- Jung Chul Kim (ORCID: https://orcid.org/0000-0001-8979-6815)
- Young Tae Kim (ORCID: https://orcid.org/0000-0002-7347-1052)
- Jung‐Yun Lee (ORCID: https://orcid.org/0000-0001-7948-1350)
- Eunhyang Park (ORCID: https://orcid.org/0000-0003-2658-5054)
- Yong Jae Lee (ORCID: https://orcid.org/0000-0003-0297-3116)
- Sunghoon Kim (ORCID: https://orcid.org/0000-0002-1645-7473)
Institutions
- Yonsei University (KR)
- Severance Hospital (KR)
- Yonsei University Health System (KR)
Publication Details
- Journal
- BMC Cancer
- Published
- 2024-12-29
- DOI
- https://doi.org/10.1186/s12885-024-13294-3
- Citations
- 5
- Primary Topic
- Endometrial and Cervical Cancer Treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.91