Microwave-assisted acetylation of alcohols, phenols, and amines using phthalimide-N-sulfonic acid as an organo-catalyst under solvent-free conditions

An efficient, environmentally benign, and simple procedure has been developed for acetylation of various alcohols, phenols and amines.In this method, Phthalimide-N-sulfonic acid is used as a new and effective organocatalyst in catalytic amount.This procedure was carried out under solvent-free conditions at room temperature as well as at microwave irradiation.Microwave-assisted reaction gives improved yields with a reduced reaction time.The present method provides noteworthy advantages of microwave irradiation and organo-catalyst such as simple work-up procedure, short reaction time with excellent yields and environmentally benign procedure.All compounds have been confirmed by 1 H NMR, 13 C NMR and IR spectroscopy.