Discovery of anti-Ebola virus multi-target inhibitors from traditional Chinese medicine database using molecular screening, biophysical investigation, and binding free energy calculations
Our findings provide valuable insights into the molecular mechanisms driving the efficacy of TCM drugs against EBOV and suggest novel approaches for the development of anti-EBOV therapies.
Authors
- Abbas Khan (ORCID: https://orcid.org/0000-0002-4288-7602)
- Fahad M. Alshabrmi (ORCID: https://orcid.org/0000-0001-5827-6040)
- Dong‐Qing Wei (ORCID: https://orcid.org/0000-0003-4200-7502)
- Tarek Benameur (ORCID: https://orcid.org/0000-0002-3762-3223)
- Anwar Mohammad (ORCID: https://orcid.org/0000-0001-6318-8707)
- Abrar Mohammad Sayaf (ORCID: https://orcid.org/0000-0002-9766-2531)
- Abdelali Agouni (ORCID: https://orcid.org/0000-0002-8363-1582)
- Kar Kheng Yeoh
Institutions
- Universiti Sains Malaysia (MY)
- Qassim University (SA)
- Shanghai Jiao Tong University (CN)
- Buraydah Colleges (SA)
- Dasman Diabetes Institute (KW)
- King Faisal University (SA)
- Qatar University (QA)
- Sunway University (MY)
Publication Details
- Journal
- Journal of Infection and Public Health
- Published
- 2024-12-30
- DOI
- https://doi.org/10.1016/j.jiph.2024.102636
- Citations
- 5
- Primary Topic
- Viral Infections and Outbreaks Research
- Type
- article
- Field-Weighted Citation Impact
- 1.95
Funders
- Fonds National de la Recherche Luxembourg
- Qatar University
- Qatar National Research Fund