Circulating large extracellular vesicles as diagnostic biomarkers of indeterminate thyroid nodules: multi-platform omics analysis
Circulating large extracellular vesicle miRNA and protein profiles have a high diagnostic value to discriminate between benign and malignant nodules for patients with Thy3f cytology. Further validation for clinical performance will be needed.
Authors
- Alaa Abdelsalam (ORCID: https://orcid.org/0009-0008-7990-6302)
- Mohammad Eddama (ORCID: https://orcid.org/0000-0002-4582-0788)
- Nada Ahmed (ORCID: https://orcid.org/0000-0002-2849-9961)
- Kevin Beatson (ORCID: https://orcid.org/0000-0001-5824-5009)
- Rijan Gurung (ORCID: https://orcid.org/0000-0002-2400-4220)
- Tarek Abdel‐Aziz (ORCID: https://orcid.org/0000-0001-7630-9985)
- Lucie H. Clapp (ORCID: https://orcid.org/0000-0001-7802-4481)
- Georges Iskandar
- Richard A. Cohen (ORCID: https://orcid.org/0000-0003-2227-8460)
- Abdulrahman Alomar (ORCID: https://orcid.org/0009-0000-2766-8383)
- Jigisha Patel (ORCID: https://orcid.org/0000-0001-6877-0130)
Institutions
- University College London Hospitals NHS Foundation Trust (GB)
- Royal London Hospital (GB)
- University College London (GB)
- Alexandria University (EG)
Publication Details
- Journal
- BJS Open
- Published
- 2024-12-30
- DOI
- https://doi.org/10.1093/bjsopen/zrae139
- Citations
- 4
- Primary Topic
- Thyroid Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.43
Funders
- University College London Hospitals NHS Foundation Trust