Ondansetron as a Cause of Transient Blindness: A Case Report

REPORTpantoprazole 40 mg IV twice a day, injection ondansetron 4 mg thrice a day, tablet amlodipine 10 mg twice a day, and tablet baclofen 25 mg twice a day.The patient was improving with the treatment and was mobilized out of bed on the 3rd day of admission.However, on the 4th day of admission, the patient suddenly complained of a loss of vision.Her vitals were normal, and no other abnormality was detected.The patient had been administered intravenous ondansetron 4 mg 10 minutes prior to the onset of blindness.The patient experienced vertigo and sudden blackout, with everything appearing greenish.A neurology consultation was sought.The neurological examination was normal, other than the blindness.However, the patient was agitated and restless.A provisional diagnosis of encephalopathy/acute psychosis was made.Color Doppler of carotid and vertebral vessels was normal.The electroencephalogram was also normal, as was the noncontrast magnetic resonance imaging (MRI) brain.Other laboratory investigations, such as serum electrolytes, serum calcium, albumin, magnesium, and thyroid stimulating hormone (TSH), were normal.