Integrated multi-omics analysis reveals clinical significance of hepatocyte nuclear factor-1β in tumor immune microenvironment, immunotherapy and prognostic prediction for colon adenocarcinoma
This study clarifies the role of HNF1B in the treatment of colon adenocarcinoma. This study provides a foundation for further in-depth mechanistic studies and proposes new directions for optimizing immunotherapy strategies for colon adenocarcinoma.
Authors
- Fushan Gao
- H H He (ORCID: https://orcid.org/0000-0001-7934-6976)
- Hongcai Yang (ORCID: https://orcid.org/0000-0001-6622-8778)
- Yibo Gao (ORCID: https://orcid.org/0000-0002-0501-9814)
- Wenlin Gong (ORCID: https://orcid.org/0000-0002-8070-6235)
- Jie He (ORCID: https://orcid.org/0000-0002-7564-9176)
- Fei Shao (ORCID: https://orcid.org/0009-0003-6413-9933)
- Zhen Zhang (ORCID: https://orcid.org/0009-0006-8239-6652)
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Beijing Chao-Yang Hospital, Capital Medical University (CN)
- National Cancer Center (US)
Publication Details
- Journal
- Cancer Immunology Immunotherapy
- Published
- 2024-12-30
- DOI
- https://doi.org/10.1007/s00262-024-03870-8
- Citations
- 1
- Primary Topic
- Pancreatic and Hepatic Oncology Research
- Type
- article
- Field-Weighted Citation Impact
- 0.28
Funders
- National Natural Science Foundation of China
- Sanming Project of Medicine in Shenzhen
- National Key Research and Development Program of China
- Special Project for Research and Development in Key areas of Guangdong Province
- Chinese Academy of Medical Sciences Initiative for Innovative Medicine