Downregulated METTL3 Accumulates TERT Expression that Promote the Progression of Ovarian Endometriosis
Together, our study identified a new molecular mechanism that underlies the pathogenesis of endometriosis. Inhibition of m6A modification and of the METTL3/TERT axis may enhance cellular proliferation and migration, thereby contributing to the progression of endometriosis.
Authors
- Hua Tao
- Yushan Li (ORCID: https://orcid.org/0000-0003-0019-5891)
- Yini Wei
- Fang Li (ORCID: https://orcid.org/0009-0002-4588-3030)
- Nie Lifang
- Junkai Chang
- Ru Meng (ORCID: https://orcid.org/0000-0001-5290-9791)
- Yu Zhang (ORCID: https://orcid.org/0000-0001-8296-154X)
Institutions
- Changzhi Medical College (CN)
- Liuzhou Maternal and Child Health Hospital (CN)
- Yancheng Third People's Hospital (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- Frontiers in Bioscience-Landmark
- Published
- 2024-12-18
- DOI
- https://doi.org/10.31083/j.fbl2912421
- Citations
- 3
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.70