VPO1 Promotes Programmed Necrosis of Cardiomyocytes in Rats with Chronic Heart Failure by Upregulating CYLD
VPO1 exacerbates cardiomyocyte programmed necrosis in CHF rats by upregulating CYLD, which activates the RIPK1/RIPK3/MLKL signaling pathway. Thus, VPO1 may represent a potential therapeutic target for CHF.
Authors
- Yinzhuang Zhang (ORCID: https://orcid.org/0009-0004-1416-5356)
- Fang Li (ORCID: https://orcid.org/0009-0002-5458-1106)
- Zhijie Shen
- Dan Huang (ORCID: https://orcid.org/0009-0002-4835-2112)
- Chonghua Lou
- Z. Mao
Institutions
- Central South University (CN)
Publication Details
- Journal
- Frontiers in Bioscience-Landmark
- Published
- 2024-12-24
- DOI
- https://doi.org/10.31083/j.fbl2912425
- Citations
- 3
- Primary Topic
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.72
Funders
- Natural Science Foundation of Hunan Province