Recent Advancement in Capsule: Emerging Novel Technologies and Alternative Shell Materials for Wide Range of Therapeutic Needs

Advancements in capsule technology are revolutionizing drug delivery by enhancing therapeutic efficacy, patient compliance, and precision medicine. This review examines innovative capsule systems, including the Novel Floating Ring Capsule for extended gastric retention, Telemetric Capsules for real-time health monitoring, and CODAS for circadian rhythm-based drug release. Technologies such as Innercap's capsule-in-capsule design, SODAS® and DUOCAP® for controlled and sustained release, and hydrogel-based and hydrophilic sandwich capsules for targeted delivery are discussed. These cutting-edge capsules offer improved stability, targeted release, and multi-phase delivery, paving the way for personalized and more effective therapeutic options.