Factors affecting the return of spontaneous circulation in cardiac arrest patients

The aim of this study was to determine the factors affecting the return of spontaneous circulation (ROSC) in cardiac arrest patients who underwent quality chest compressions as recommended by international guidelines. In this retrospective observational study, the data of nontraumatic out-of-hospital cardiac arrest (OHCA) patients (n = 784) brought by an ambulance to emergency between January 2018 and December 2019 were extracted from the validated hospital automation system. About 452 patients met inclusion criteria. All eligible patients for analysis were treated with an automatic cardiopulmonary resuscitation (CPR) device for chest compression.. Significance threshold for P-value was < 0.05. Logistic regression analysis was used to determine the factors affecting mortality. 61.7% (n = 279) of the study population was male and 65.0% of patients (n = 294) had OHCA. 88 patients (19.5%) had a shockable rhythm and were defibrillated. There was a 0.5-fold increase in mortality rate in patients with thrombocyte count < 199 × 109/L (OR: 0.482, 95% CI: 0.280-0.828) and CPR duration longer than 42 minutes led to a 6.2-fold increase in the probability of ROSC (OR: 6.232, 95% CI: 3.551-10.936) (P < .05). There is no clear consensus on the ideal resuscitation duration; however, our study suggests that it should last at least 42 minutes.