Photodriven Site-Selective Deuteration of Pyridyl Ketones with Deuterium Oxide
Abstract In this work, a photodriven phosphine/D2O-mediated method for the reductive deuteration of pyridyl ketones was developed. By regulating the reaction conditions, site-selective deuteration of pyridyl diketones was achieved with high deuterium-incorporation rates.
Authors
- Kaiwu Dong (ORCID: https://orcid.org/0000-0001-6250-2629)
- Chaoren Shen (ORCID: https://orcid.org/0000-0002-2849-7990)
- Wan‐Fa Tian (ORCID: https://orcid.org/0000-0003-1873-5366)
- Yanzhong Li (ORCID: https://orcid.org/0000-0002-2898-3075)
Institutions
- East China Normal University (CN)
Publication Details
- Journal
- Synlett
- Published
- 2024-12-30
- DOI
- https://doi.org/10.1055/a-2509-0121
- Primary Topic
- Chemical Reactions and Isotopes
- Type
- article
- Field-Weighted Citation Impact
- 0.00