Epidemiology of S. aureus Non-Susceptible to Vancomycin in Western Asia

Staphylococcus aureus is considered among the most severe hazardous bacteria, especially, after the emergence of methicillin-resistant Staphylococcus aureus, that associated with significant levels of pathogenicity along with mortality. Vancomycin is the treatment of choice for methicillin-resistant Staphylococcus aureus infections worldwide. Unfortunately, Vancomycin non-susceptible Staphylococcus aureus strains have also emerged, making controlling Staphylococcus aureus infections an international health challenge. The availability of accurate epidemiological information from all over the world aids in developing the best surveillance and control programs, limiting the spread and evolution of infections. In this paper, we review the mechanism of vancomycin non-susceptibility among Staphylococcus aureus and focus on the emergence, epidemiological characteristics, and the latest progress in Western Asia.