A Bibliometric and Visual Analysis of Publications on Low-Density Lipoprotein Cholesterol Estimating Equations

The concentration of low-density lipoprotein cholesterol (LDL-C) is recognized as a crucial factor in cardiovascular health. This study aims to conduct a comprehensive bibliometric and visual analysis to provide a comprehensive review of current research trends and patterns in this research area. We retrieved the publications from the Web of Science (WoS) database and conducted the bibliometric analyses using VOSviewer software, bibliometrix R package, and biblioshiny web tool. The analysis was conducted on 620 original articles and review papers published between 1990 and 2023 from institutions located in 62 different countries and published in 329 journals. The countries with the most articles were the US, China, and Japan. The most productive journals were Clinica Chemica Acta, Clinical Biochemistry, and Clinical Chemistry; while the most cited journals were Clinical Chemistry, Circulation, and JAMA-Journal of the American Medical Association. The co-occurrence network visualizations of keywords and terms provided a global overview of LDL-C estimating equations. The study presented provides valuable insights into potential research avenues within the examined field, serving as a foundation for future research initiatives.