Nigrosporinol Sulfoxides A and B, Sulfur-Bridged Heterocyclic Sesquiterpenoids Produced by Cultures of the Fungus <i>Nigrospora lacticolonia</i>
The sesquiterpenoids nigrosporinol sulfoxides A (<b>1</b>) and B (<b>2</b>) have been isolated from cultures of the endophytic fungus <i>Nigrospora lacticolonia</i> harvested from the sunchoke <i>Helianthus tuberosus</i> L. collected in Thailand. Nigrosporinol sulfoxides A (<b>1</b>) and B (<b>2</b>) have 4/5/5/5/7 heterocyclic skeletons <b>3</b> featuring a sulfoxide bridge not previously found in a terpenoid natural product from any living source.
Authors
- Raymond J. Andersen (ORCID: https://orcid.org/0000-0002-7607-8213)
- Kwanjai Kanokmedhakul (ORCID: https://orcid.org/0000-0002-3237-2920)
- Sophon Boonlue (ORCID: https://orcid.org/0000-0002-2411-6863)
- Apisara Somteds
- Thanapat Suebrasri
- Brian O. Patrick (ORCID: https://orcid.org/0000-0002-2921-8439)
- Somdej Kanokmedhakul (ORCID: https://orcid.org/0000-0001-8481-2636)
Institutions
- University of British Columbia (CA)
- Khon Kaen University (TH)
Publication Details
- Journal
- Organic Letters
- Published
- 2024-12-30
- DOI
- https://doi.org/10.1021/acs.orglett.4c04304
- Citations
- 2
- Primary Topic
- Microbial Natural Products and Biosynthesis
- Type
- article
- Field-Weighted Citation Impact
- 0.90
Funders
- Khon Kaen University
- Thailand Research Fund