Transcriptome of Capsular Contracture around Breast Implants Mimics Allograft Rejection: A Matched Case–Control Study
This study identified key genes associated with capsular contracture, suggesting new drug candidates (eg, MMP1 inhibitors) to improve breast implant surgery outcomes. Synergizing research on allograft rejection and capsular contracture could also lead to new treatment strategies.
Authors
- Thomas Bjarnsholt (ORCID: https://orcid.org/0000-0002-8003-7414)
- Mathilde N. Hemmingsen (ORCID: https://orcid.org/0000-0002-8439-6537)
- Mathias Ørholt (ORCID: https://orcid.org/0000-0002-8815-8392)
- Mikkel Herly (ORCID: https://orcid.org/0000-0002-5866-1173)
- Erik Eiler Frydshou Bak (ORCID: https://orcid.org/0009-0006-1802-9153)
- Andreas Haahr Larsen (ORCID: https://orcid.org/0000-0002-2230-2654)
- Blaine Gabriel Fritz (ORCID: https://orcid.org/0000-0002-2085-894X)
- Anders Woetmann (ORCID: https://orcid.org/0000-0002-3008-735X)
- John Tran (ORCID: https://orcid.org/0000-0001-7065-0381)
- Peter Vester‐Glowinski
- Tim K. Weltz (ORCID: https://orcid.org/0000-0003-1432-3479)
- Thomas Litman (ORCID: https://orcid.org/0000-0002-6068-901X)
Institutions
- University of Copenhagen (DK)
- Copenhagen University Hospital (DK)
- Rigshospitalet (DK)
- Plastic Surgery Hospital (CN)
- LEO Foundation (DK)
- Centre for Omic Sciences (ES)
Publication Details
- Journal
- Plastic & Reconstructive Surgery
- Published
- 2024-12-24
- DOI
- https://doi.org/10.1097/prs.0000000000011938
- Citations
- 6
- Primary Topic
- Breast Implant and Reconstruction
- Type
- article
- Field-Weighted Citation Impact
- 3.44
Funders
- Lundbeckfonden
- Novo Nordisk
- Rigshospitalet
- H. Lundbeck A/S