Association of Sleep Spindle Rate With Memory Consolidation in Children With Rolandic Epilepsy
Children with RE have impaired sleep-dependent memory consolidation during the active period of disease that correlates with a deficit in the sleep spindle rate. This finding identifies a noninvasive biomarker to aid diagnosis and a potential etiologic mechanism to guide therapeutic discovery of cognitive dysfunction in RE and related sleep-activated epilepsy syndromes.
Authors
- Hunki Kwon (ORCID: https://orcid.org/0000-0003-4189-2546)
- Wen Shi (ORCID: https://orcid.org/0000-0003-1022-6639)
- Jonathan F. Huang
- Erin D. Berja
- Catherine J. Chu (ORCID: https://orcid.org/0000-0001-7670-9313)
- Dhinakaran M. Chinappen (ORCID: https://orcid.org/0000-0002-0980-3120)
- Katherine G. Walsh (ORCID: https://orcid.org/0000-0002-4459-5507)
- Dara S. Manoach (ORCID: https://orcid.org/0000-0001-9208-1167)
- Elizabeth A. Kinard
- Mark Kramer (ORCID: https://orcid.org/0000-0002-9979-7202)
- Skyler K. Goodman (ORCID: https://orcid.org/0009-0004-5103-6027)
Institutions
- Boston University (US)
- Harvard University (US)
- Massachusetts General Hospital (US)
- Athinoula A. Martinos Center for Biomedical Imaging (US)
- Center for Systems Biology (US)
Publication Details
- Journal
- Neurology
- Published
- 2024-12-30
- DOI
- https://doi.org/10.1212/wnl.0000000000210232
- Citations
- 11
- Primary Topic
- Sleep and Wakefulness Research
- Type
- article
- Field-Weighted Citation Impact
- 3.77