INTEGRATING EXERCISE AND REHABILITATION IN RHEUMATOLOGY: ADVANCING THERAPEUTIC STRATEGIES FOR OPTIMAL PATIENT OUTCOMES

This review examines the integration of exercise and rehabilitation into rheumatologic care, highlighting their synergistic effects alongside pharmacological treatment. Exercise modalities such as aerobic, resistance, and flexibility training enhance physical function, alleviate pain, and reduce systemic inflammation, primarily through the activity of exercise-induced myokines which support immune regulation and tissue repair. Despite demonstrated benefits, adoption is hindered by barriers, including limited adherence, healthcare access, and absence of standardized guidelines. This review suggests personalized exercise protocols, interdisciplinary collaboration, and telehealth innovations to promote accessibility and adherence. Expanding exercise and rehabilitation as standard practices in rheumatology may optimize patient outcomes and long-term disease management, with future research needed to refine protocols and validate rehabilitation strategies.