Bidirectional recurrent neural network approach for predicting cervical cancer recurrence and survival

Cervical cancer is a deadly disease in women globally. There is a greater chance of getting rid of cervical cancer in case of earliest diagnosis. But for some patients, there is a chance of recurrence. The chances of treating the Recurrence of cervical carcinoma arelimited. The main objective of a research is to find the key features that will predict the cervical cancer recurrence and survival rates accurately by utilizing a neural network that is bidirectionally recurrent. The goal is to reduce risk factors of cervical cancer recurrence by identifying genes with positive coefficients and targeting them for preventive interventions. First step is identification of risk factors for cervical carcinoma recurrence by utilising clinical attributes. This research uses following Random forest, Logistic regression, Gradient boosting and support vector machine algorithms are applied for classification. Random forest offers the maximum precision of these four techniques at 91.2%. The second step is identifying long noncoding RNA (lnRNA) gene signatures among people with cervical carcinomaby implementingHSIC model. Intended to discover biomarkers in initial cervical carcinoma clinical data from people who experienced a distant repetition that could be connected to lnRNA gene signatures and utilized for forecasting survival rates using a bidirectional recurrent neural network(Bi-RNN). The results shows that Bi-RNN model effectively forecast the cervical cancer recurrence and survival.

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Publication Details

Journal
Scientific Reports
Published
2024-12-30
DOI
https://doi.org/10.1038/s41598-024-80472-5
Citations
5
Primary Topic
Cancer-related molecular mechanisms research
Type
article
Field-Weighted Citation Impact
1.43

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article

Bidirectional recurrent neural network approach for predicting cervical cancer recurrence and survival

Jaehyuk Cho, V E Sathishkumar, S. Geeitha, K.P. Rama Prabha
5 citations
Scientific Reports
Cancer-related molecular mechanisms research
1.43
article

Bidirectional recurrent neural network approach for predicting cervical cancer recurrence and survival

Jaehyuk Cho, V E Sathishkumar, S. Geeitha, K.P. Rama Prabha
article en
5 citations

Abstract

Cervical cancer is a deadly disease in women globally. There is a greater chance of getting rid of cervical cancer in case of earliest diagnosis. But for some patients, there is a chance of recurrence. The chances of treating the Recurrence of cervical carcinoma arelimited. The main objective of a research is to find the key features that will predict the cervical cancer recurrence and survival rates accurately by utilizing a neural network that is bidirectionally recurrent. The goal is to reduce risk factors of cervical cancer recurrence by identifying genes with positive coefficients and targeting them for preventive interventions. First step is identification of risk factors for cervical carcinoma recurrence by utilising clinical attributes. This research uses following Random forest, Logistic regression, Gradient boosting and support vector machine algorithms are applied for classification. Random forest offers the maximum precision of these four techniques at 91.2%. The second step is identifying long noncoding RNA (lnRNA) gene signatures among people with cervical carcinomaby implementingHSIC model. Intended to discover biomarkers in initial cervical carcinoma clinical data from people who experienced a distant repetition that could be connected to lnRNA gene signatures and utilized for forecasting survival rates using a bidirectional recurrent neural network(Bi-RNN). The results shows that Bi-RNN model effectively forecast the cervical cancer recurrence and survival.

Scientific ReportsVol. 14(1)
M. Kumarasamy College of Engineering, Jeonbuk National University (KR), Sunway University (MY), Vellore Institute of Technology University (IN)
Ministry of Environment, Korea Environmental Industry and Technology Institute
Openalex Percentile: Top 17%
Cancer-related molecular mechanisms research
1.43
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