Understanding MASH: An Examination of Progression and Clinical Outcomes by Disease Severity in the TARGET-NASH Database

Progression to all-cause mortality in patients with MASH was significantly associated with the presence of higher fibrosis stage and cirrhosis. Cardiometabolic comorbidities such as T2D and hypertension were prevalent in patients with MASH progression. Early identification and management of MASH may mitigate disease progression and liver-related complications.

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Publication Details

Journal
Advances in Therapy
Published
2024-12-30
DOI
https://doi.org/10.1007/s12325-024-03085-4
Citations
6
Primary Topic
Liver Disease Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
2.32
Controls
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article

Understanding MASH: An Examination of Progression and Clinical Outcomes by Disease Severity in the TARGET-NASH Database

Rakesh Luthra, Aakash Sheth
6 citations
Advances in Therapy
Liver Disease Diagnosis and Treatment
2.32
article

Understanding MASH: An Examination of Progression and Clinical Outcomes by Disease Severity in the TARGET-NASH Database

Rakesh Luthra, Aakash Sheth
article en
6 citations

Abstract

Progression to all-cause mortality in patients with MASH was significantly associated with the presence of higher fibrosis stage and cirrhosis. Cardiometabolic comorbidities such as T2D and hypertension were prevalent in patients with MASH progression. Early identification and management of MASH may mitigate disease progression and liver-related complications.

Advances in TherapyVol. 42(2)
Novo Nordisk (United States) (US)
Openalex Percentile: Top 10%
Liver Disease Diagnosis and Treatment
2.32
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