Personalized modeling of gut microbiome metabolism throughout the first year of life
Our simulations elucidate the metabolic capabilities of the infant gut microbiome demonstrating they are altered in Cesarian section delivery at the earliest time points. Our workflow can be readily applied to other cohorts to evaluate the effect of feeding type, or maternal factors such as diet on host-gut microbiome inactions in early life.
Authors
- Jean‐Louis Guéant (ORCID: https://orcid.org/0000-0002-5067-042X)
- Almut Heinken (ORCID: https://orcid.org/0000-0001-6938-8072)
- Paul Wilmes (ORCID: https://orcid.org/0000-0002-6478-2924)
- Susheel Bhanu Busi (ORCID: https://orcid.org/0000-0001-7559-3400)
- Rola Shaaban
Institutions
- Inserm (FR)
- University of Luxembourg (LU)
- UK Centre for Ecology & Hydrology (GB)
- Centre de Recherche en Automatique de Nancy (FR)
- Nutrition-Génétique et Exposition aux Risques Environnementaux (FR)
- Université de Lorraine (FR)
- Nantes Université (FR)
Publication Details
- Journal
- Communications Medicine
- Published
- 2024-12-30
- DOI
- https://doi.org/10.1038/s43856-024-00715-4
- Citations
- 7
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 1.64
Funders
- European Commission
- Agence Nationale de la Recherche
- Fonds National de la Recherche Luxembourg