Adaptation of Escherichia coli to ciprofloxacin and enrofloxacin: Differential proteomics of the SOS response and RecA-independent mechanisms
The results demonstrate that the slight structural variation between ciprofloxacin and enrofloxacin leads to unique proteomic adaptations. These findings suggest that even subtle chemical differences can lead to distinct adaptive trajectories and illustrate the flexibility of cellular stress responses.
Authors
- Benno H. ter Kuile (ORCID: https://orcid.org/0000-0002-8523-8135)
- Chiara Varriale
- Raymond Pasman
- Johan Bengtsson‐Palme (ORCID: https://orcid.org/0000-0002-6528-3158)
- Sam Luitwieler
- Lisa Teichmann
Institutions
- Amsterdam University of Applied Sciences (NL)
- University of Gothenburg (SE)
- University of Amsterdam (NL)
Publication Details
- Journal
- International Journal of Antimicrobial Agents
- Published
- 2024-12-30
- DOI
- https://doi.org/10.1016/j.ijantimicag.2024.107420
- Citations
- 7
- Primary Topic
- Bacterial Genetics and Biotechnology
- Type
- article
- Field-Weighted Citation Impact
- 3.85