Acute Liver Failure and Human Herpesvirus 6 Infection: Reactivation in Immunoparesis?
This ALF has a viral cause due to a possible reactivation of HHV-6 in the context of immunoparesis secondary to malnutrition and binge drinking, though we cannot exclude a contribution from a toxic cause due to paracetamol overuse, facilitated by these same susceptibility factors. HHV-6 should be included in the differential diagnosis of ALF of undetermined cause, particularly in immunocompromised and seriously ill patients.
Authors
- Jandira Lima
- Maria Adriana Henriques (ORCID: https://orcid.org/0000-0003-0288-6653)
- D. Ferreira (ORCID: https://orcid.org/0000-0002-2949-2059)
- Ana Isabel Rodrigues (ORCID: https://orcid.org/0000-0001-9140-9722)
- Maria Augusta Cipriano (ORCID: https://orcid.org/0000-0003-3736-0141)
- Isabel Correia (ORCID: https://orcid.org/0000-0002-0809-3040)
Institutions
- OncoMed (United States) (US)
- Instituto Politécnico de Leiria (PT)
- Hospitais da Universidade de Coimbra (PT)
- Administração Regional de Saúde de Lisboa e Vale do Tejo (PT)
Publication Details
- Journal
- GE Portuguese Journal of Gastroenterology
- Published
- 2024-12-30
- DOI
- https://doi.org/10.1159/000543325
- Citations
- 2
- Primary Topic
- Liver Disease and Transplantation
- Type
- article
- Field-Weighted Citation Impact
- 0.74
Funders
- Universidade de Coimbra