Central Nervous System Tumor-Embryonal Tumors Type With Neuroendocrine Differentiation

The central nervous system (CNS) tumor with embryonal tumors type is a rare type of CNS tumor with lack of unifying genetic alterations or diagnostic markers. The CNS tumor-embryonal tumors (CETs) have limited therapeutic options with high probability of adverse events associated with conventional treatment. Identification of somatostatin receptor expression and/or prostate-specific membrane antigen expression in CET patients by using PET/CT imaging may be helpful for deciding therapeutic approaches in these patients as theranostics. We present a 56-year-old woman who complained of headache, diminution of vision, and diagnosed CET and demonstrated high SSTR expression on PET/CT imaging, indicating peptide receptor radionuclide therapy could be effective therapeutic option in this case.

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Journal
Clinical Nuclear Medicine
Published
2024-12-30
DOI
https://doi.org/10.1097/rlu.0000000000005655
Primary Topic
Neuroblastoma Research and Treatments
Type
article
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article

Central Nervous System Tumor-Embryonal Tumors Type With Neuroendocrine Differentiation

Rahul V. Parghane, Sandip Kanti Basu, Yeshwanth Edamadaka
Clinical Nuclear Medicine
Neuroblastoma Research and Treatments
article

Central Nervous System Tumor-Embryonal Tumors Type With Neuroendocrine Differentiation

Rahul V. Parghane, Sandip Kanti Basu, Yeshwanth Edamadaka
article en

Abstract

The central nervous system (CNS) tumor with embryonal tumors type is a rare type of CNS tumor with lack of unifying genetic alterations or diagnostic markers. The CNS tumor-embryonal tumors (CETs) have limited therapeutic options with high probability of adverse events associated with conventional treatment. Identification of somatostatin receptor expression and/or prostate-specific membrane antigen expression in CET patients by using PET/CT imaging may be helpful for deciding therapeutic approaches in these patients as theranostics. We present a 56-year-old woman who complained of headache, diminution of vision, and diagnosed CET and demonstrated high SSTR expression on PET/CT imaging, indicating peptide receptor radionuclide therapy could be effective therapeutic option in this case.

Clinical Nuclear MedicineVol. 50(4)
Bhabha Atomic Research Centre (IN), Homi Bhabha National Institute (IN), Tata Memorial Hospital (IN)
Good health and well-being
Openalex Percentile: Top 62%
Neuroblastoma Research and Treatments
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Central Nervous System Tumor-Embryonal Tumors Type With Neuroendocrine Differentiation — Rahul V. Parghane, Sandip Kanti Basu, et al. · Clinical Nuclear Medicine (2024) | TGRS Research Map | TGRS