Single-cell and spatial transcriptomic analyses reveal heterogeneity characteristics and specific cell subtype regulators in growth hormone-secreting pituitary adenomas
GHPA exhibits rich heterogeneity and diverse cell subtypes, with specific transcription factors potentially regulating cell malignant bias, thereby influencing tumor characteristics and prognosis.
Authors
- Mingzhao Zhang (ORCID: https://orcid.org/0000-0003-0491-0063)
- Pinan Liu
- Xin Ma (ORCID: https://orcid.org/0000-0003-2340-991X)
- Zetian Mi (ORCID: https://orcid.org/0000-0001-9494-7390)
- Xingcheng Yi (ORCID: https://orcid.org/0000-0002-6594-1851)
- Zhijun Yang (ORCID: https://orcid.org/0000-0002-9873-2036)
- Lizhen Ma (ORCID: https://orcid.org/0000-0002-8259-2972)
- Yanwen Zhang (ORCID: https://orcid.org/0000-0003-1833-3885)
- Lifeng Wang (ORCID: https://orcid.org/0000-0001-5095-6842)
- Weijia Zhi
- Hongyu Wu (ORCID: https://orcid.org/0009-0005-5958-1545)
- Cong Fu (ORCID: https://orcid.org/0000-0002-9042-5736)
- Zhenqi Yang (ORCID: https://orcid.org/0009-0004-8331-8686)
Institutions
- Capital Medical University (CN)
- Jilin University (CN)
- Beijing Tian Tan Hospital (CN)
- Beijing Institute of Neurosurgery (CN)
- First Hospital of Jilin University (CN)
- Beijing Radiation Center (CN)
Publication Details
- Journal
- International Journal of Surgery
- Published
- 2024-12-30
- DOI
- https://doi.org/10.1097/js9.0000000000002178
- Citations
- 3
- Primary Topic
- Pituitary Gland Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.07