Phyto-phospholipid Complex Vesicles:A Revolutionary Approach for Enhancing Bioavailability and Optimizing Therapeutic Potential in Herbal Medicine

The medicinal potential of phytoconstituents obtained from plants is widely recognized. Whole-plant extracts or isolated phytoconstituents have been shown through experiments to exhibit a variety of medicinal potentials, including antibacterial, neurologically protective, liver-protective properties, an antioxidant and skin-protective properties. Although these phytoconstituents offer potential therapeutic effects, their usage is restricted due to inadequate bioavailability, persistence in physiological fluids, and authenticity problems. These remain unresolved issues that impact the use of these priceless traditional herbal remedies in the efficient management and treatment of a range of medical ailments. Phytoconstituents’ loading in phospholipid-based vesicular systems may be a way to tackle these challenging issues. The goal of this review is to summarize phyto-phospholipid vesicles and some of their relevant uses in drug delivery systems, as well as to emphasize the relationship between properties and applications, as well as the effect of phospholipid species on drug delivery efficiency. Based on the findings of various research investigations, this literature review attempts to investigate why Phyto-phospholipid vesicles are considered as the best nanotechnology in delivery systems for drugs. Optimal absorption and utilization of nutraceuticals and herbal medications can be enhanced by the process of Phyto phospholipid complexation.