Fenfluramine treatment for Dravet syndrome: Long term real‐world analysis demonstrates safety and reduced health care burden
FFA is well tolerated, without cardiac toxicity, and reduces treatment load and HCRU, suggesting improved patient management. BMI reduction in young children highlights the need for growth and nutritional monitoring.
Authors
- Nicola Pietrafusa (ORCID: https://orcid.org/0000-0003-2446-796X)
- Michela Quintiliani (ORCID: https://orcid.org/0000-0002-8278-6953)
- Renzo Guerrini (ORCID: https://orcid.org/0000-0002-7272-7079)
- Francesca Ragona (ORCID: https://orcid.org/0000-0003-1399-8271)
- Alessandra Boncristiano (ORCID: https://orcid.org/0000-0003-4270-5781)
- Francesca Darra (ORCID: https://orcid.org/0000-0002-1062-8438)
- Domenica Battaglia (ORCID: https://orcid.org/0000-0003-0491-4021)
- M. Luigia Gambardella
- Viola Doccini (ORCID: https://orcid.org/0000-0002-5166-8401)
- Marina Trivisano (ORCID: https://orcid.org/0000-0002-9841-8581)
- Eliana Parente (ORCID: https://orcid.org/0000-0001-8177-8292)
- Tiziana Granata (ORCID: https://orcid.org/0000-0002-0170-6836)
- Antonella Riva (ORCID: https://orcid.org/0000-0001-9152-5571)
- Simona Balestrini (ORCID: https://orcid.org/0000-0001-5639-1969)
- Nicola Specchio (ORCID: https://orcid.org/0000-0002-8120-0287)
- Rita Monni
- Sara Matricardi (ORCID: https://orcid.org/0000-0002-4403-6342)
- Pasquale Striano (ORCID: https://orcid.org/0000-0002-6065-1476)
- Carla Marini (ORCID: https://orcid.org/0000-0002-9212-2691)
- Alberto Cossu (ORCID: https://orcid.org/0000-0001-6945-6151)
Institutions
- Università Cattolica del Sacro Cuore (IT)
- University of Verona (IT)
- Istituto Giannina Gaslini (IT)
- University of Chieti-Pescara (IT)
- Fatebenefratelli Hospital (IT)
- Meyer Children's Hospital (IT)
- Bambino Gesù Children's Hospital (IT)
- Music Conservatory of Mantova (IT)
- University of the Sacred Heart (JP)
- ASST Fatebenefratelli Sacco (IT)
- Fondazione IRCCS Istituto Neurologico Carlo Besta (IT)
- Ospedali Riuniti Umberto I (IT)
- Azienda Ospedaliera Carlo Poma (IT)
- University of Florence (IT)
- University of Genoa (IT)
- KU Leuven (BE)
Publication Details
- Journal
- Epilepsia
- Published
- 2024-12-30
- DOI
- https://doi.org/10.1111/epi.18241
- Citations
- 12
- Primary Topic
- Epilepsy research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 4.63
Funders
- Teva Pharmaceutical Industries
- Jazz Pharmaceuticals
- Zogenix
- PTC Therapeutics
- LouLou Foundation
- SK Life Science
- Ospedale Pediatrico Bambino Gesù
- Ministero della Salute
- Eisai
- H. Lundbeck A/S