Chemical probes for imaging cellular compartmentalization
Chemical probes mark cellular compartments which have distinct interior environments and membrane compositions.For examples of the former, rhodamine ester and cyanine mitotrackers label mitochondria based on their negative membrane potential and rosamine mitotrackers have a photosensitizing effect.Lysotracker probes are weakly basic fluoresceins that get trapped in the acidic lumen of late endo/lysosomes.
Authors
- Johannes Broichhagen (ORCID: https://orcid.org/0000-0003-3084-6595)
- Margret Helene Bülow (ORCID: https://orcid.org/0000-0001-6006-8507)
Institutions
- Düsseldorf University Hospital (DE)
- Leibniz-Forschungsinstitut für Molekulare Pharmakologie (DE)
- Heinrich Heine University Düsseldorf (DE)
Publication Details
- Journal
- Trends in Biochemical Sciences
- Published
- 2024-12-30
- DOI
- https://doi.org/10.1016/j.tibs.2024.12.005
- Citations
- 1
- Primary Topic
- Nanoplatforms for cancer theranostics
- Type
- article
- Field-Weighted Citation Impact
- 0.18