Implantation of Islets Co-Seeded with Tregs in a Novel Biomaterial Reverses Diabetes in the NOD Mouse Model
These studies show the efficacy of a combinatorial approach seeding Tregs with pancreatic islets in a novel self-assembling organoid for reversing T1D.
Authors
- Jamel Ali (ORCID: https://orcid.org/0000-0002-2997-1981)
- Ayane de Sá Resende (ORCID: https://orcid.org/0000-0002-6133-7091)
- Michael W. Lipscomb (ORCID: https://orcid.org/0000-0002-9700-3763)
- Tatiana de Moura
- Diana M. Elizondo
- Dazhi Yang (ORCID: https://orcid.org/0000-0003-0316-8346)
- Ricardo Luís Louzada da Silva (ORCID: https://orcid.org/0000-0002-5294-1203)
- Laís Lima de Oliveira Rekowsky
- Jonathan Seenarine
Institutions
- University of Minnesota (US)
- Florida A&M University - Florida State University College of Engineering (US)
- Universidade Federal de Sergipe (BR)
- MacroGenics (United States) (US)
- University of Minnesota Medical Center (US)
- University of Maryland, Baltimore County (US)
Publication Details
- Journal
- Tissue Engineering and Regenerative Medicine
- Published
- 2024-12-30
- DOI
- https://doi.org/10.1007/s13770-024-00685-7
- Citations
- 1
- Primary Topic
- Pancreatic function and diabetes
- Type
- article
- Field-Weighted Citation Impact
- 0.57
Funders
- National Science Foundation
- U.S. Department of Defense
- National Institutes of Health
- National Institute of General Medical Sciences
- National Institute of Diabetes and Digestive and Kidney Diseases