Targeting the lysine lactylome for the treatment of glioma
The anomalous activation of glycolysis and subsequent accumulation of L-lactate under aerobic conditions, known as the Warburg effect, are prominent metabolic hallmarks of cancer[1][1]. Extensive research has revealed that lactate acts not only as an energy-supplying substrate but also as a
Authors
- Guanzhang Li (ORCID: https://orcid.org/0000-0002-0353-5751)
- Tao Jiang (ORCID: https://orcid.org/0000-0002-7008-6351)
- Wei Zhang (ORCID: https://orcid.org/0000-0002-1631-6486)
- Di Wang (ORCID: https://orcid.org/0009-0009-1545-1641)
Institutions
- Capital Medical University (CN)
- Beijing Tian Tan Hospital (CN)
- National Clinical Research Center for Digestive Diseases (CN)
- Beijing Institute of Neurosurgery (CN)
- Chinese Institute for Brain Research (CN)
Publication Details
- Journal
- Cancer Biology and Medicine
- Published
- 2024-12-30
- DOI
- https://doi.org/10.20892/j.issn.2095-3941.2024.0461
- Citations
- 4
- Primary Topic
- Cancer, Hypoxia, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 1.14
Funders
- National Natural Science Foundation of China
- Beijing Municipal Health Commission