Alterations in gut-derived uremic toxins before the onset of azotemic chronic kidney disease in cats

Impaired gut-derived uremic toxin handling is apparent at least 6 months before the diagnosis of azotemia, likely reflecting an already ongoing decrease in GFR, tubular function, or both. A direct causal relationship between gut-derived uremic toxicity and the initiation of CKD in cats is still lacking.

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Publication Details

Journal
Journal of Veterinary Internal Medicine
Published
2024-12-30
DOI
https://doi.org/10.1111/jvim.17289
Citations
5
Primary Topic
Dialysis and Renal Disease Management
Type
article
Field-Weighted Citation Impact
1.70

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article

Alterations in gut-derived uremic toxins before the onset of azotemic chronic kidney disease in cats

Ellen Vanden Broecke, Lynn Vanhaecke, Ellen De Paepe, Laurens Van Mulders et al.
5 citations
Journal of Veterinary Internal Medicine
Dialysis and Renal Disease Management
1.70
article

Alterations in gut-derived uremic toxins before the onset of azotemic chronic kidney disease in cats

Ellen Vanden Broecke, Lynn Vanhaecke, Ellen De Paepe, Laurens Van Mulders, Sylvie Daminet, Femke Mortier
article en
5 citations

Abstract

Impaired gut-derived uremic toxin handling is apparent at least 6 months before the diagnosis of azotemia, likely reflecting an already ongoing decrease in GFR, tubular function, or both. A direct causal relationship between gut-derived uremic toxicity and the initiation of CKD in cats is still lacking.

Journal of Veterinary Internal MedicineVol. 39(1)
Queen's University Belfast (GB), Ghent University (BE)
EveryCat Health Foundation, Fonds Wetenschappelijk Onderzoek, Universiteit Gent, Bijzonder Onderzoeksfonds UGent
Good health and well-being
Openalex Percentile: Top 13%
Dialysis and Renal Disease Management
1.70
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Alterations in gut-derived uremic toxins before the onset of azotemic chronic kidney disease in cats — Ellen Vanden Broecke, Lynn Vanhaecke, et al. · Journal of Veterinary Internal Medicine (2024) | TGRS Research Map | TGRS