Unveiling the Cytological Enigma of Malignant Spindle Cell Neoplasm of Peripheral Nerve Sheath: A Clinicopathological Image

Peripheral Nerve Sheath (PNS) tumours are rare neoplasms arising from deeper soft tissues, peripheral nerves, perineural cells, or Schwann cells with ectomesenchymal origins [1]. The incidence rate is between 4-13%, with the upper extremity being the most commonly involved site (45%) [2]. The role of Fine Needle Aspiration Cytology (FNAC), based on the cytomorphology of these neoplasms of the PNS, is challenging and often confusing, underscoring the complex diagnostic nature of the lesions. Therefore, FNAC details were highlighted by presenting a clinicopathological image and providing insight into the intricate cytomorphology involved.

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Publication Details

Journal
JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH
Published
2024-12-30
DOI
https://doi.org/10.7860/jcdr/2025/75618.20434
Primary Topic
Neurofibromatosis and Schwannoma Cases
Type
article
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article

Unveiling the Cytological Enigma of Malignant Spindle Cell Neoplasm of Peripheral Nerve Sheath: A Clinicopathological Image

Jayashree Bhawani, Shreya Giri Goswami, Poornima Pandey
JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH
Neurofibromatosis and Schwannoma Cases
article

Unveiling the Cytological Enigma of Malignant Spindle Cell Neoplasm of Peripheral Nerve Sheath: A Clinicopathological Image

Jayashree Bhawani, Shreya Giri Goswami, Poornima Pandey
article en

Abstract

Peripheral Nerve Sheath (PNS) tumours are rare neoplasms arising from deeper soft tissues, peripheral nerves, perineural cells, or Schwann cells with ectomesenchymal origins [1]. The incidence rate is between 4-13%, with the upper extremity being the most commonly involved site (45%) [2]. The role of Fine Needle Aspiration Cytology (FNAC), based on the cytomorphology of these neoplasms of the PNS, is challenging and often confusing, underscoring the complex diagnostic nature of the lesions. Therefore, FNAC details were highlighted by presenting a clinicopathological image and providing insight into the intricate cytomorphology involved.

JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH
Openalex Percentile: Top 62%
Neurofibromatosis and Schwannoma Cases
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