Terbinafine Resistance in <i>Trichophyton</i> Species From Patients With Recalcitrant Infections Detected by the <scp>EUCAST</scp> Broth Microdilution Method and <scp>DermaGenius</scp> Resistance Multiplex <scp>PCR</scp> Kit

Terbinafine resistance was detected in 52% of Trichophyton isolates from recalcitrant infections by the EUCAST broth microdilution. T. rubrum was the most common species among the resistant isolates (81.3%). The DermaGenius Resistance Multiplex PCR kit was a reliable tool for the detection of mutations associated with terbinafine resistance and is suitable as an initial screening for terbinafine resistance before results from EUCAST broth microdilution testing is available. Susceptibility testing of Trichophyton spp. from skin and nail samples is highly relevant from patients with terbinafine treatment failure.