PENGARUH EKSTRAK ETANOL DAUN MANGKOKAN (Nothopanax scutellarium) YANG DIMANFAATKAN SEBAGAI ANTIBAKTERI DARI BAKTERI Vibrio sp

One of the pathogenic bacteria found in aquatic environments is Vibrio sp., which causes vibriosis. The use of mangkokan leaf extract as an antibacterial agent against Vibrio has not been studied before. The aim of this research was to evaluate the antibacterial activity of mangkokan leaf extract in inhibiting the growth of Vibrio sp. The antibacterial test in this study used the disc diffusion method. In addition, the study also conducted tests for yield and phytochemical analysis. The results showed that mangkokan leaf extract at concentrations of 100% and 75% exhibited moderate antibacterial activity, with average inhibition zone diameters of 8.5 mm and 6.35 mm, respectively. The yield of the ethanol extract from mangkokan leaves was 10.2%. The mangkokan leaf extract contains secondary metabolites such as flavonoids, steroids, alkaloids, tannins, and saponins.